Read The Epigenetics Revolution Online

Authors: Nessa Carey

Tags: #Science/Life Sciences/Genetics and Genomics

The Epigenetics Revolution (50 page)

of eggs
cytosine (C)
 
Dacogen see
2-aza-5´-deoxycytidine
Darwin, Charles
de novo DNA methylation
DEMETER
deoxyribose nucleic acid
see
DNA
depression
dermo-abrasion
developmental biology
developmental programming
DGCR8
DGCR8
gene
diabetes
type 1
type 2
diallyl disulphide
diet
see also
nutrition
differentiation
DiGeorge syndrome
dimethyl sulfoxide (DMSO)
diploid genome
discordance
Dlk1-Dio3
region
DMSO
DNA
double helix
as double-stranded
as script
editing
reading
as zip
DNA demethylation
active
passive
DNA methylation
age-related changes
in
agouti
mice
in ants
in cancer
de novo
decrease in response to stimulus
histone modifications and
in honeybees
and imprinting
inhibition by 5-azacytidine
in mammals
and parent-of-origin effect
in plants
and stress
DNA methyltransferase
see
DNMTs
DNA methyltransferase inhibitors (DNMT inhibitors)
in cancer treatment
and Yamanaka factor efficiency
DNA replication
DNMT1
DNMT1 inhibitors
Dnmt3
Dnmt3
gene
DNMT3A
DNMT3B
DNMT3L
DNMTs
Dolly the Sheep
dosage compensation
Down’s syndrome
Drosophila melanogaster see
fruitflies
Duchenne muscular dystrophy
duck-billed platypus
Dutch Hunger Winter
dystrophin
 
echidna
ectodysplasin-A
editing
Edwards, Robert
eggs
cytoplasm of
embryonic stem (ES) cells
endosperm
environmental toxins
environmentally enriched conditions
epidermal growth factor
epidermis
epigenetic enzymes, inhibition
epigenetic landscape
epigenetic mosaics
epigenetic therapies
see also
cell therapy; gene therapy
‘epigenetic transmission’
epigenetics, molecular description
epigenomes
epithelial cells
eplilepsy
ES cells
Esteller, Manel
European swallow
evolution, theory of
evolutionary imperative
exons
EZH2
 
famines
fat cells
fat metabolism
FD
gene
fear
fibroblasts
Fire, Andrew
FLC
FLC
gene
FLC
gene promoter
Fleming, Alexander
flies
Florey, Howard
FLOWERING LOCUS C
(
FLC
) gene
flowering plants
see
plants
flowers
foetal alcohol syndrome
folic acid
Franklin, Rosalind
Fraser, Peter
fraternal twins, DNA methylation patterns
Friend, Charlotte
frog
fruitflies
FT
gene
 
G9a enzyme
gametes
imprints during production
gatekeepers
Gdnf
gene
gene expression, changes in
gene repression
gene silencing, post-transcriptional
gene therapy
genes
body
numbers
genome sequencing
genomes
genotypes
germ cells
germline
GlaxoSmithKline
glial cell-derived neurotrophic factor
see Gdnf
gene
glial cells
glucose
gonads
Gordon, Peter
Grb10
Grb10
gene
Great Chinese Famine
Greider, Carol
guanine (G)
Gurdon, John
Lasker Prize
as Nobel Prize candidate
 
H2A
H2B
H3
H3K4
H3K27
H4
haematological tumours
haemoglobin
haploid genome
HDAC inhibitors
and Yamanaka factor efficiency
HDAC1
HDAC2
HDACs
healthy living
heart disease
heat stroke
Hepburn, Audrey
hereditary cystatin C amyloid angiopathy
hippocampus
Hirundo rustica
histone acetyltransferase
histone codes
histone deacetylases
see
HDACs
histone modifications
in cancer
DNA methylation and
in plants
repressive
and stress
histone octamer
histone tails
histones
honeybees
CpG motifs
DNA methylation
genome
histone modification
larvae
memory
see also
queen bees; worker bees
hormonal signalling
Horvitz, Robert
HOTAIR
RNA
HOX
genes
HOX-C
cluster
HOX-D
cluster
human chromosome 11
human chromosome 15
human chromosome 21
human chromosome 22
human genome, protein-coding regions
human life extension
humpback salmon
Huntington’s disease
Huxley, Thomas Henry
hydatidiform moles
(E)-10-hydroxy-2-decenoic acid (10HDA)
hydroxyl
5-hydroxymethylcytosine
hypothalamus
hypotheses, disproving
 
IAP retrotransposons
ibuprofen
Iceland
identical twins
DNA methylation patterns
IGF2
IGF2
gene
Igf2r
Igf2r
gene
immune responses
imprinted chromosomes
imprinting
addition and removal process
disorders in
DNA methylation and
in flowering plants
long ncRNAs in
imprinting control regions
in vitro fertilisation
induced pluripotent stem (iPS) cells
infertility
inflammatory responses
inherited factors
inner cell mass (ICM)
inosine (I)
insulin
insulin-like growth factor 2
(
Igf2
) gene
insulin pathway
International Society of Aesthetic Plastic Surgery
intra-uterine environment
introns
iPS cells
Issa, Jean-Pierre
Istodax
see
romidepsin
 
Jacob, François
Jaenisch, Rudolph
patents
Jones, Peter
junk DNA
Just-So
stories
Juvenile Hormone
 
Kabuki syndrome
Kammerer, Paul
kangaroo
karyotypes
45, X
47, XXX
47, XXY
kidney cancer
kidney toxicity
kilobase (kb)
King, Thomas
Kipling, Rudyard
Klf4
gene
Klinefelter’s syndrome
Kuhn, Thomas
 
Laird, Peter
Lamarck, Jean-Baptiste
Lander, Eric
Lasker Prize
Lee, Jeannie
Lego
let-7
RNA
leucine (L)
leukaemia
libido loss
LIN-14
LIN-14
gene
Lin28
liver
living organisms, complexity
lizards
LSD1
lung cancer
non-small cell
Lwoff, André
Lyon, Mary
Lyonisation
lysine (K)
on H3 tail
lysine 9
lysine 56
lysosomal iduronate-2-sulfatase
 
macroH2A
maggots
malarial parasites
Maleszka, Ryszard
malnutrition
mammalian reproduction
mammals
egg-laying
placental
Marks, Paul
marsupials
maternal health, importance
Meaney, Michael
mechanistic explanations
MeCP2
MeCP2
gene
MEFs
melanocyte stem cells
melanocytes
Mello, Craig
memory
long-term
short-term
Mendel, Gregor
mental illness, development
mental retardation

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