Secondary Schizophrenia (2 page)

Randwick, New South Wales, Australia
vii

Contributors

Stanley V. Catts

Matt P. Galloway PhD

Professor

Department of Psychiatry and Behavioral
School of Medicine,

Neurosciences,

The University of Queensland;

Neuropsychiatry Division,

and Mental Health Centre,

Wayne State University School of Medicine,
The Royal Brisbane and Women’s Hospital,
Detroit, Michigan, USA

Herston, Queensland, Australia

Bangalore N. Gangadhar MD

Vibeke S. Catts BS MD FRANZCP

Professor and Head

School of Medicine,

Department of Psychiatry,

The University of Queensland,

National Institute of Mental Health and
St. Lucia, Queensland, Australia

Neurosciences (NIMHANS),

Bangalore, India

Jennifer M. Connolly BSc (Hons)

Research Manager

Wayne Hall BSc (Hons) PhD AM

Kavanagh Research Group,

Professor of Public Health Policy

Institute of Health and Biomedical Innovation,
School of Population Health,

Queensland University of Technology,
University of Queensland,

Brisbane, Queensland, Australia

Herston, Queensland, Australia

David L. Copolov MB BS PhD DPM MPM FRACP

Malcolm Hopwood MD FRANZCP

FRANZCP

Director

Professor of Psychiatry

Veterans’ Psychiatry Unit;

Monash University;

and Director,

and Professor of Psychiatry

Brain Disorders Program,

University of Melbourne,

Heidelberg Repatriation Hospital,

Melbourne, Australia

Heidelberg West, Victoria, Australia
Michael D. Jibson MD PhD

Louisa Degenhardt BA (Hon) (Psych) MPsychol

Professor

(Clinical) PhD

Director of Residency Education,

Professor of Epidemiology

Department of Psychiatry,

National Drug and Alcohol Research Centre,
University of Michigan,

University of New South Wales,

Ann Arbor, Michigan, USA

Randwick, New South Wales, Australia
Ripu D. Jindal MD

Stewart L. Einfeld MD DCH FRANZCP

University of Pittsburgh School of Medicine,
Chair of Mental Health

Pittsburgh, Pennsylvania, USA

Faculty of Health Sciences;

Senior Scientist

David J. Kavanagh

Brain and Mind Research Institute,
Professor

University of Sydney,

School of Psychology and Counselling;
Sydney, New South Wales, Australia
and Institute of Health and Biomedical Innovation,
Queensland University of Technology,
Anthony Feinstein MPhil PhD FRCPC

Brisbane, Queensland, Australia

Professor

Department of Psychiatry,

Sophie Kavanagh BMed FRANZCP

Sunnybrook Health Sciences Centre,
Croydon Health Group,

University of Toronto,

Sydney South West Area Health Service,
viii

Toronto, Ontario, Canada

Croydon, New South Wales, Australia
Contributors

Matcheri S. Keshavan

Leslie Lester-Burns, BS

Stanley Cobb Professor

Mercer University College of Liberal Arts
and Vice Chair for Public Psychiatry
Macon, Georgia, USA

Department of Psychiatry,

Beth Israel Deaconess Medical Center,
Lyn-May Lim MB BS MPsych FRANZCP Cert POA

and the Massachusetts Mental Health Center,
St. George’s Hospital,

Harvard Medical School,

Kew, Victoria, Australia

Boston, Massachusetts, USA

Ennapadam S. Krishnamoorthy MD PhD FRCP

Jeffrey C. L. Looi MBBS FRANZCP MRACMA

Director and TS Srinivasan Chair

Director

The Institute of Neurological Sciences,
Research Centre for the Neurosciences of Ageing
Voluntary Health Services Hospital,
(RESCENA);

Chennai, India

and Associate Professor and Deputy Head
Academic Unit of Psychological Medicine,
Rajeev Kumar MD FRANZCP PhD

Australian National University Medical School,
Assistant Professor and Consultant Psychiatrist
The Canberra Hospital,

Consultation-Liaison Psychiatry Unit, and
Canberra, Australia

Academic Unit of Psychological Medicine,
Yong Loo Lin School of Medicine,

Michael Mazurek MD

National University of Singapore,

Associate Professor

Singapore, Singapore

Department of Neurology,

Alexander F. Kurz MD

McMaster University,

Head

Hamilton, Ontario, Canada

Department of Psychiatry and Psychotherapy,
Klinikum rechts der Isar,

Serge A. Mitelman MD

Technische Universität Munchen,

Assistant Professor of Psychiatry

Munich, Germany

Mount Sinai School of Medicine,

Neuroscience Positron Emission Tomography
Nicola T. Lautenschlager MD FRANZCP

Laboratory,

Professor and Chair of Psychiatry of Old Age
New York, New York, USA

Department of Psychiatry,

University of Melbourne,

Ramon Mocellin MB BS MSc MMed FRANZCP

St. George’s Campus,

Consultant Neuropsychiatrist

St. Vincent’s Hospital,

Neuropsychiatry Unit,

Kew, Victoria, Australia

Royal Melbourne Hospital;

Western Australian Centre for Health and Ageing
Research Fellow

(WACHA);

Melbourne Neuropsychiatry Centre,

School of Psychiatry and Clinical Neurosciences,
University of Melbourne,

University of Western Australia,

Melbourne, Australia

Perth, Australia

Edward C. Lauterbach MD FANPA DFAPA

Bryan Mowry MB BS BA (Hons) MD FRANZCP

Professor of Psychiatry, Neurology and Radiology;
Professor

Director

Queensland Brain Institute,

Neurodegenerative Disease Program;
University of Queensland,

Chief

Brisbane, Queensland, Australia;

Division of Adult and Geriatric Psychiatry,
and Executive Director

Department of Psychiatry and Behavioral Sciences,
Queensland Centre for Mental Health Research,
Mercer University School of Medicine,
The Park – Centre for Mental Health,
Macon, Georgia, USA

Wacol, Queensland, Australia

ix

Contributors

Kim T. Mueser PhD

Vandana Shashi MD

Professor of Psychiatry and Community and Family
Assistant Professor of Pediatrics

Medicine

Department of Pediatrics,

Dartmouth Medical School,

Section on Medical Genetics,

Hanover, New Hampshire, USA

Wake Forest University School of Medicine,
Winston-Salem, North Carolina, USA
Anand K. Pandurangi MBBS MD

Professor of Psychiatry, Medical Director, and
Arabella Smith MBBS DipRCPath FHGSA FRCPA

Chairman

Department of Cytogenetics,

Division of Inpatient Psychiatry,

Children’s Hospital Westmead,

Virginia Commonwealth University,

Westmead, New South Wales, Australia
Richmond, Virginia, USA

Sergio E. Starkstein MD FRANZCP

Eric M. Pihlgren PhD

Professor of Psychiatry

Department of Psychiatry and Behavioral
School of Psychiatry,

Neurosciences,

University of Western Australia

Neuropsychiatry Division

Perth, Australia

Wayne State University School of Medicine
Detroit, Michigan, USA

Ezra S. Susser MD

Department Chair, Epidemiology,

Seethalakshmi Ramanathan MBBS DPM

and Anna Cheskis Gelman and Murray Charles
Clinical Research Fellow

Gelman Professor of Epidemiology

Department of Psychiatry,

Mailman School of Public Health;

KEM Hospital,

Professor of Psychiatry

Mumbai, India

College of Physicians and Surgeons;
and Co-Director

Patricia I. Rosebush MScN MD FRCP(C)

Statistics and Epidemiology,

Professor

HIV Center for Clinical and Behavior Studies
Department of Psychiatry and Behavioural
(NYSPI),

Neurosciences,

New York, New York, USA

McMaster University,

Hamilton, Ontario, Canada

Rajiv Tandon MD

Professor of Psychiatry

Perminder S. Sachdev MD PhD FRANZCP

University of Florida College of Medicine,
Scientia Professor of Neuropsychiatry
McKnight Brain Institute,

School of Psychiatry

Gainesville, Florida, USA

University of New South Wales;

Director

Jagadisha Thirthalli MD

Neuropsychiatric Institute,

Associate Professor of Psychiatry

Prince of Wales Hospital,

National Institute of Mental Health and
Randwick, New South Wales, Australia
Neurosciences (NIMHANS),

Bangalore, India

Richard D. Sanders MD

Associate Professor

Bruce J. Tonge MBBS MD DPM FRANZCP

Departments of Psychiatry and Neurology,
Professor

Boonschoft School of Medicine and Wright State
Centre for Developmental Psychiatry and
University

Psychology,

and the VA Medical Center

Monash University,

Dayton, Ohio, USA

Clayton, Victoria, Australia

x

Contributors

Julian Trollor MB BS MD FRANZCP MFPOA

Mark Walterfang MB BS (Hons) FRANZCP

Chair, Intellectual Disability Mental Health
Consultant Neuropsychiatrist

School of Psychiatry, University of New South Wales;
Neuropsychiatry Unit,

and Staff Specialist

Royal Melbourne Hospital;

Neuropsychiatric Institute,

and Research Fellow

Prince of Wales Hospital, Euroa Centre,
Neuroimaging Laboratory,

Randwick, New South Wales, Australia
Melbourne Neuropsychiatry Centre, University of
Melbourne,

Dennis Velakoulis MB BS FRANZCP

Carlton South, Victoria, Australia
Clinical Director

Melbourne Neuropsychiatry Centre,

Jane Zhang PhD

North Western Mental Health and

Mount Sinai School of Medicine,

University of Melbourne;

New York, New York, USA

Director

Neuropsychiatry Unit,

Royal Melbourne Hospital,

Parkville, Victoria, Australia

xi

For any mental health researcher, finding the cause
you that the brain responds to many injuries and
of schizophrenia would be the ultimate prize. The
threats with this response. It could be electrical dis-impact of schizophrenia on our society is immense.

charges, traumatic injury, subtle beginnings of neuro-Even though it is a low-prevalence disorder relative
degeneration, or the effects of psychoactive drugs. The
to depression and anxiety disorders, it has captured
list is mind-boggling, and each presents a slightly dif-the focus of most psychiatric services worldwide. It
ferent mechanism of its causation. Could it be that the
devastates individuals in the prime of their lives and
brain has a limited repertoire of responses to multi-overwhelms families by its persistent challenge to most
ple challenges, and schizophrenia is that final path-things we hold dear about our social existence. For
way? The hope of this book is that many little secrets
researchers, it is the ultimate challenge and the most
about schizophrenia will be revealed so that there is
frustrating snare. It has a bewitching presence that
nowhere for it to hide. Psychiatry has a proud tradition
many find too tempting to resist. Yet, it gives away few
of arguing about terminology, but I decided to stick
secrets. Neuropathologists, who recognize that it is a
with the DSM-IV refuge of secondary schizophrenia in
brain disease, have long regarded it as their graveyard.