Pocket Medicine: The Massachusetts General Hospital Handbook of Internal Medicine

Pocket
   MEDICINE
Fifth Edition
Edited by
M
ARC
S. S
ABATINE
, MD, MPH
A
SSOCIATE
P
ROFESSOR OF
M
EDICINE
H
ARVARD
M
EDICAL
S
CHOOL

 

 

 

 

 

The Massachusetts General Hospital
Handbook of Internal Medicine
Health
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Library of Congress Cataloging-in-Publication Data
Pocket medicine (Sabatine) Pocket medicine / [edited by] Marc S. Sabatine. — Fifth edition.

p. ; cm.

Preceded by Pocket medicine / edited by Marc S. Sabatine. 4th ed.
c2011.

Includes bibliographical references and index.

ISBN-13: 978-1-4511-8237-8

ISBN-10: 1-4511-8237-6

ISBN-13: 978-1-4511-8887-5

ISBN-10: 1-4511-8887-0

I. Sabatine, Marc S., editor of compilation. II. Title.

[DNLM: 1. Internal Medicine–Handbooks. 2. Clinical Medicine–Handbooks. WB 39]

RC55

616–dc23

2013019655

DISCLAIMER
Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of the information in a particular situation remains the professional responsibility of the practitioner.

The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug.

Some drugs and medical devices presented in the publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in their clinical practice.

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10 9 8 7 6 5 4 3 2 1

CONTENTS

Contributing Authors

Foreword

Preface

CARDIOLOGY

Neal A. Chatterjee
,
Ada Stefanescu, William J. Hucker, David M. Dudzinski, Marc S. Sabatine, Michelle O’Donoghue
Electrocardiography

Chest Pain

Noninvasive Evaluation of CAD

Coronary Angiography and Revascularization

Acute Coronary Syndromes

PA Catheter and Tailored Therapy

Heart Failure

Cardiomyopathies

Valvular Heart Disease

Pericardial Disease

Hypertension

Aortic Aneurysms

Acute Aortic Syndromes

Arrhythmias

Atrial Fibrillation

Syncope

Intracardiac Devices

Cardiac Risk Assessment for Noncardiac Surgery

Peripheral Artery Disease

PULMONARYQ

Ian J. Barbash, Kathryn A. Hibbert, Atul Malhotra

Dyspnea

Pulmonary Function Tests

Asthma

Anaphylaxis

Chronic Obstructive Pulmonary Disease

Hemoptysis

Bronchiectasis

Solitary Pulmonary Nodule

Obstructive Sleep Apnea

Interstitial Lung Disease

Pleural Effusion

Venous Thromboembolism

Pulmonary Hypertension

Respiratory Failure

Mechanical Ventilation

Acute Respiratory Distress Syndrome

Sepsis

GASTROENTEROLOGY

Zachary A. Zator
,
Andrew S. de Lemos, Lawrence S. Friedman
Esophageal and Gastric Disorders

Gastrointestinal Bleeding

Diarrhea, Constipation and Ileus

Diverticular Disease

Inflammatory Bowel Disease

Intestinal Ischemia

Pancreatitis

Abnormal Liver Tests

Hepatitis

Acute Liver Failure

Cirrhosis

Hepatic Vascular Disease

Ascites

Biliary Tract Disease

NEPHROLOGY

Andrew S. Allegretti, Andrew L. Lundquist, Hasan Bazari
Acid-Base Disturbances

Sodium and Water Homeostasis

Potassium Homeostasis

Renal Failure

Glomerular Disease

Urinalysis

Nephrolithiasis

HEMATOLOGY-ONCOLOGY

Andrew M. Brunner, Sheheryar K. Kabraji, Mark M. Awad, Andrew J. Aguirre, Daniel J. DeAngelo, David P. Ryan
Anemia

Disorders of Hemostasis

Platelet Disorders

Coagulopathies

Hypercoagulable States

Disorders of Leukocytes

Transfusion Therapy

Myelodysplastic Syndromes

Myeloproliferative Neoplasms

Leukemia

Lymphoma

Plasma Cell Dyscrasias

Hematopoietic Stem Cell Transplantation

Lung Cancer

Breast Cancer

Prostate Cancer

Colorectal Cancer

Chemotherapy Side Effects

Pancreatic Tumors

Oncologic Emergencies

Cancer of Unknown Primary Site

INFECTIOUS DISEASES

Ana A. Weil, Emily P. Hyle, Nesli Basgoz

Pneumonia

Fungal Infections

Infections in Immunosuppressed Hosts

Urinary Tract Infections

Soft Tissue and Bone Infections

Infections of the Nervous System

Bacterial Endocarditis

Tuberculosis

HIV/AIDS

Tick-Borne Diseases

Fever Syndromes

ENDOCRINOLOGY

Kelly
B. Lauter, Marc N. Wein, Michael Mannstadt

Pituitary Disorders

Thyroid Disorders

Adrenal Disorders

Calcium Disorders

Diabetes Mellitus

Lipid Disorders

RHEUMATOLOGY

Zachary S. Wallace, Eli Miloslavsky, Robert P. Friday
Arthritis—Overview

Rheumatoid Arthritis

Adult Onset Still’s Disease & Relapsing Polychondritis

Crystal Deposition Arthritides

Seronegative Spondyloarthritis

Infectious Arthritis & Bursitis

Connective Tissue Diseases

Systemic Lupus Erythematosus

Vasculitis

IgG4-Related Disease

Cryoglobulinemia

Amyloidosis

NEUROLOGY

Michael P. Bowley, Todd M. Herrington, Eyal Y. Kimchi, Sarah Wahlster, Tracey A. Cho
Change in Mental Status

Seizures

Alcohol Withdrawal

Stroke

Weakness & Neuromuscular Dysfunction

Headache

Back and Spinal Cord Disease

CONSULTS

Kiran H. Lagisetty, Jennifer F. Tseng, Katherine T. Chen, Stella K. Kim
Surgical Issues

Ob/Gyn Issues

Ophthalmic Issues

APPENDIX

ICU Medications & Treatment of Hypotension/Shock

Antibiotics

Formulae and Quick Reference

ABBREVIATIONS

INDEX

PHOTO INSERTS

Radiology

Echocardiography & Coronary Angiography

Peripheral Blood Smears & Leukemias

Urinalysis

ACLS

CONTRIBUTING AUTHORS

Andrew J. Aguirre, MD, PhD

Hematology-Oncology Fellow, Dana-Farber/Partners CancerCare Hematology/Oncology Program
Andrew S. Allegretti, MD
Internal Medicine Resident, Massachusetts General Hospital

Mark M. Awad, MD, PhD

Hematology-Oncology Fellow, Dana-Farber/Partners CancerCare Hematology/Oncology Program
Ian J. Barbash, MD
Internal Medicine Resident, Massachusetts General Hospital

Nesli Basgoz, MD

Associate Chief and Clinical Director, Infectious Disease Division, Massachusetts General Hospital Associate Professor of Medicine, Harvard Medical School

Hasan Bazari, MD

Clinical Director, Nephrology Unit, Massachusetts General Hospital Program Director, Internal Medicine Residency, Massachusetts General Hospital Associate Professor of Medicine, Harvard Medical School

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